Home Grand Prix marked by changing track conditions.
The arrival of light rain during the early part of the race disrupted Aprilia’s plans. During the seventh lap, worsening weather forced both Noale-based riders to return to the pits for a bike change to wet setup. However, shortly after, the rain stopped, requiring Espargaró and Viñales to pit again to switch back to slicks. Maverick Viñales attempted to make a comeback, but the double pit stop penalized him, relegating him to sixteenth place. Aleix Espargaró, also affected by the double bike change, retired on the fifteenth lap.